Diaminopyrimine oxide ngezinwele

Iyini i-diaminopyrimidine oxide?
I-Unodial (igama lamakhemikhali: i-diaminopyrimidine oxide) iyinhlanganisela elwa nokulahlekelwa izinwele enciphisa i-follicle fibrosis yezinwele ngokuvimbela inkulumo ye-lysyl hydroxylase mRNA, isebenze i-hair follicle vasodilation, nokuvikela amangqamuzana e-papilla ezinwele ekucindezelekeni kwe-oxidative kanye nokuvuselela i-androgen. Ivame ukutholakala kumafomula e-shampoo elwa nokulahlekelwa izinwele aphezulu.
Ingabe i-Pyrrolidinyl diaminopyrimidine oxide ukukhula kwezinwele?
I-Diaminopyrimidine oxide isiza ukuthambisa i-collagen futhi ingasetshenziswa emikhiqizweni yokunakekelwa kwezinwele ukwelapha ukulahleka kwezinwele okubangelwa ukulahleka kwezimpande zezinwele ngaphambi kwesikhathi. Ivimbela umsebenzi we-lysine hydroxylase futhi ivimbele i-fibrosis. I-Lysine hydroxylase hydroxylates i-lysine endaweni ye-telopeptide ye-collagen, okwenza ama-molecule e-collagen abe nzima ukuwohloka futhi abangele ukuthi anqwabelane. Ukuqoqwa kwe-collagen kuholela ekuqineni nasekuncipheni kwezinhlayiya zezinwele ezizungezile, okuholela ku-fibrosis nokunciphisa ukukhula kwe-follicle yezinwele. Iphinde ivimbele umsebenzi we-5α-reductase, ngaleyo ndlela inciphise ukuguqulwa kwe-testosterone ku-dihydrotestosterone. Ilungele ukusetshenziswa kumafutha ezinwele, ama-conditioner, ama-tonics ezinwele, ama-shampoos, izifutho zezinwele, kanye nokwelapha ukulahleka kwezinwele kwesizini.