5 Amainolevulinic acid methyl ester hydrokeride (5-ala)

5 Aminolevulinic Acid Methyl Ester Hydrochloride phofo ke eng?5-ALA-HCL）

5 Aminolevulinic Acid Methyl Ester Hydrochloride phofo ke ester derivative, e ka sebelisoang tšimong ea meriana le botle. 5-Aminolevulinic acid methyl ester hydrochloride ke lithethefatsi tse sebelisetsoang ho phekola maemo a letlalo a kang psoriasis, dermatitis le vitiligo. E sebelisoa ho phekola mofetše oa letlalo le ho ruruha mafu a kang lupus erythematosus.(1)

5 Aminolevulinic Acid Methyl Ester Hydrochloride Features
✔ Bohloeki bo phahameng - ho sebelisa theknoloji e tsoetseng pele ea synthesis ho netefatsa bohloeki bo phahameng le botsitso ba sehlahisoa.
✔ Motsoako o motle oa ho qhibiliha ha metsi - o qhibiliha habonolo ka metsing le ka har'a metsoako ea tlhaho, e bonolo ho etsoa le ho sebelisoa.
✔ Bioavailability e phahameng - sebopeho sa methyl esterification se ntlafatsa ho kenella ha sele le ho thusa ho ntlafatsa ts'ebetso.
✔ Lisebelisoa tse fapaneng - li loketse likarolo tsa lipatlisiso tsa meriana, litlolo le tsa baeloji.

5 Aminolevulinic Acid Methyl Ester Hydrochloride Application
5-aminolevulinate methyl ester hydrochloride phofo e ka laola mosebetsi oa melanocyte le ho fokotsa tlhahiso ea melanin. E ka ama ts'ebetso ea tyrosinase, e leng enzyme ea bohlokoa ts'ebetsong ea melanin synthesis, ho thibela sebopeho sa melanin, e le hore matheba a letlalo a nyamele butle-butle, ho fihlela phello ea ho soeufala.(2)

5-aminolevulinic acid assid methyl elter hydrocreddy e na le thepa e matla ea antioxidant, e ka tlosang li-radicals mahala 'meleng, tse kang superoxide anion free radicals, hydroxyl free radicals, joalo-joalo Li-radicals tsena tsa mahala li hlasela li-macromolecules tsa likokoana-hloko tse kang lipids, liprotheine le DNA liseleng tsa letlalo, tse lebisang ho senyeha ha lisele le botsofali. Ka ho tlosa li-radicals tsa mahala, o ka fokotsa karabelo ea khatello ea oxidative, oa sireletsa lisele tsa letlalo ho senya, 'me oa liehisa mokhoa oa ho tsofala ha letlalo.

5-aminolevulinate methyl ester hydrochloride phofo e susumetsa mosebetsi oa letlalo la fibroblasts le ho eketsa collagen synthesis. Collagen ke karolo e ka sehloohong ea letlalo, e fanang ka elasticity le ho tiea. Ha re ntse re tsofala, motsoako oa collagen o fokotseha butle-butle, 'me letlalo le tla bontša matšoao a botsofali a kang ho sagging le wrinkles. 5-aminolevulinate methyl ester hydrochloride e ka khothalletsa motsoako oa collagen, ho boloka elasticity le ho tiea ha letlalo, le ho fokotsa moloko oa wrinkles.

Ke eng 5 Aminolevulinic Acid Methyl Ester Hydrochloride phofo sebelisoa bakeng sa?

5 Aminolevulinic Acid Methyl Ester Hydrochloride e sebelisoa ka phekolo ea photodynamic (phekolo e bobebe) ho phekola actinic keratosis (AK) sefahlehong le letlalong..

Melemo ea 5 Aminolevulinic Acid Methyl Ester Hydrochloride phofo?

Ho feta moo, 5 Aminolevulinic Acid Methyl Ester Hydrochloride phofo ke ha e na feela antioxidant effect, empa hape e na le phello e hatellang karabelong e feteletseng ea lisele tsa 'mele tse bakang kotsi 'meleng sebakeng sa ho hlasela lintho tse tsoang kantle ho naha, ka lebaka la taolo ea HO-1 liseleng tsa 'mele.

 

5 Aminolevulinic Acid Methyl Ester Hydrochloride Patlisiso ea bongaka le tlhahlobo ea phello

Lithuto tse ngata tsa kliniki li bonts'itse hore 5-ALA-ME e sebetsa hantle kalafong ea makhopho. Mona ke tse ling tsa liphetho tsa bohlokoa tsa lipatlisiso: Phello ea kalafo ea photodynamic ho makhopho.
1. Phuputso ea kliniki ho bakuli ba nang le li-acne tse itekanetseng ho isa ho tse matla li bontšitse hore bakuli ba fumaneng phekolo ea photodynamic ea 5-ALA-ME ba ile ba fokotsa haholo palo ea li-acne, ho ruruha le li-pustules nakong ea libeke tse 4-6 ka mor'a phekolo. Ho ruruha ha letlalo la mokuli ho ne ho laoloa ka katleho, 'me tekanyo ea ho khutla ha maqoqomete e ne e le tlaase.

2. Phello ea bactericidal ea 5-ALA-ME ho Propionibacterium acnes
Lintlha tsa bongaka li bontša seo 5-ALA-ME phekolo ea photodynamic e na le phello e kholo ea ho thibela Propionibacterium acnes (P. acnes). Ka ho khantša leseli la bolelele bo itseng ba maqhubu, palo ea libaktheria sebakeng sa phekolo e fokotsehile ka hoo e ka bang 50% ~ 70%. Sephetho sena se bonts'a hore ALA-ME e khona ho laola kholo ea libaktheria letlalong le ho fokotsa sebopeho sa makhopho.

3. Ho lokisa letlalo le ho ntlafatsa leqeba
Phuputso e boetse e fumane hore ka mor'a phekolo ea photodynamic, matšoao a acne, bofubelu, ho ruruha le ho ruruha ho ile ha ntlafatsoa haholo, 'me boemo ba letlalo la bakuli ba bang bo ile ba lokisoa haholo. Haholo-holo ka mor'a hore ho ruruha ho kokobele, letlalo le boreleli le 'mala li ile tsa ntlafatsoa ka katleho.

4. Liphello tsa nako e telele
Litlhahlobo tsa bongaka li boetse li bonts'a hore 5-ALA-ME photodynamic therapy e na le nako e telele ea nako e telele ea phekolo ea li-acne. Ka mor'a nako ea phekolo, bakuli ba bangata’ maemo a letlalo a ile a lula a tsitsitse, sekhahla sa ho khutla ha makhopho se ne se le tlase, 'me tlhahiso ea oli ea letlalo butle-butle e ile ea khutlela ho tloaelehileng.

Ho boloka le ho paka
Maemo a polokelo: e tiisitsoe ebile e sirelelitsoe khanyeng, e bolokiloe ka mocheso o tlase ho boloka mosebetsi oa sehlahisoa.
Litlhaloso tsa ho paka: Litlhaloso tse fapaneng li ka fanoa ho latela litlhoko tsa bareki.