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What is the source of matrine?

Belle-mère is a bioactive ingredient extracted from the traditional Chinese medicinal plant Sophora flavescens. It is widely used in skin care products. Due to its excellent anti-inflammatory, antioxidant, antibacterial and anti-aging properties, it has become an important raw material for more and more skin care brands.

Matrine benefits

Powerful anti-inflammatory effect
Matrine extract is known for its significant anti-inflammatory effect. In skin care, it helps relieve inflammatory responses caused by various factors, such as acne, eczema, allergies, etc. By regulating the immune system, It can effectively reduce redness, heat and irritation of the skin, help soothe sensitive skin, and reduce inflammatory responses.

Antioxidant and anti-aging benefits
It has powerful antioxidant properties that scavenge free radicals and reduce oxidative damage caused by environmental stressors such as UV rays and pollution. Free radicals are one of the main causes of skin aging, and Matrine helps prevent premature aging, fine lines and wrinkles by neutralizing them. It promotes the skin’s self-repair and regeneration, helping to keep the skin youthful and radiant.

Antibacterial Effect
It also has antibacterial properties that can effectively inhibit the growth of bacteria, especially when facing skin problems such as acne, it can help reduce skin problems caused by bacterial infections. This makes it an ideal choice for treating skin problems such as acne and pimples.

Improves skin quality and repairs damaged skin
It accelerates the repair process of skin cells and helps repair skin damage caused by external factors such as environmental pollution and UV exposure. It helps maintain the skin’s natural barrier function and enhances the skin’s resistance, thereby improving overall skin quality.

Inhibits melanin production and promotes even skin tone
It also inhibits melanin production, reducing spots and uneven skin tone. By regulating melanin synthesis, it can help improve the evenness of skin tone, making the skin look brighter and clearer.

Matrine’s inhibitory effect on inflammatoire factors

The researchers used LPS (lipopolysaccharide) to induce inflammatory responses in in vitro cultured human keratinocytes (HaCaT cells) and mouse skin models, and added different concentrations of Matrine (0.01%, 0.05%, and 0.1%) to observe its anti-inflammatory effect.

Experimental results:
IL-6 (interleukin-6) levels decreased by 25.3% (0.01% Matrine), 47.6% (0.05% Matrine), 65.2% (0.1% Matrine)
TNF-α (tumor necrosis factor-α) levels decreased by 18.9% (0.01% Matrine), 41.8% (0.05% Matrine), 58.7% (0.1% Matrine)
COX-2 (cyclooxygenase-2) expression was downregulated by 52% (0.1% Matrine)

Belle-mère exhibits good anti-inflammatory effects by significantly inhibiting the expression of pro-inflammatory factors, and its anti-inflammatory effect is positively correlated with the dose.

As a natural skin care ingredient, it has become an important raw material for many skin care brands due to its anti-inflammatory, antioxidant, antibacterial and repair effects. Whether it is treating inflammatory skin diseases, improving skin aging, reducing acne, or brightening skin tone and enhancing skin barrier function, It has demonstrated powerful effects. Through its multiple skin care effects, it provides an effective care solution for sensitive skin, aging skin and problematic skin.

Recommended dosage

Skin care products such as creams, lotions, and essences:
Recommended dosage: 0.1% – 0.5%
This concentration range is usually sufficient to exert its anti-inflammatory, soothing and skin repairing effects while ensuring the mildness and safety of the product.
Masks:
Recommended dosage: 0.1%1%
For mask products that require deep repair and anti-inflammatory, the amount of matrine added can be appropriately increased to 1%, but it should not be too high to avoid excessive irritation to the skin.
Acne care products:
Recommended dosage: 0.2% – 0.5%
Due to the antibacterial and anti-inflammatory properties of it, lower concentrations are usually used in acne products to help reduce inflammation and redness caused by acne.
Anti-aging products:
Recommended dosage: 0.1% – 0.3%
As an active ingredient in anti-aging products, the concentration of matrine should not be too high. Usually, it can provide antioxidant and collagen synthesis-promoting effects at a lower concentration.

Note:

Allergy test: Although it is a natural ingredient, a patch test is recommended for sensitive skin to ensure there is no adverse reaction.

Formula optimization: It is often used in combination with other mild anti-inflammatory, moisturizing or repairing ingredients (such as hyaluronic acid, glycerin, Centella asiatica, etc.) to enhance its effect and reduce possible irritation.